The Official Parent"s Sourcebook on Haemophilus Influenzae Serotype B

A Revised and Updated Directory for the Internet Age by ICON Health Publications

Publisher: Icon Health Publications

Written in English
Cover of: The Official Parent
Published: Pages: 248 Downloads: 349
Share This
The Physical Object
Number of Pages248
ID Numbers
Open LibraryOL7581957M
ISBN 100597834156
ISBN 109780597834158

Nontypable Haemophilus influenzae has now become well established as an important pathogen in both adults and children. Recent work has identified clear distinctions between nontypable and type b strains of H. influenzae. These organisms affect different patient populations, cause different infections, present different surface antigens to the. Since the introduction of the Haemophilus influenzae serotype b (Hib) vaccine, H influenzae epidemiology in the United States has shifted; nontypeable H influenzae has emerged as the cause of most invasive disease in all age groups [].In the United States, adults aged ≥65 years now account for the largest proportion of H influenzae disease, and the risk of disease increases with increasing.   Scheifele D, Halperin S, Law B, et al. Invasive Haemophilus influenzae type b infections in vaccinated and unvaccinated children in Canada, CMAJ. Jan 4. (1) Starner TD, Zhang N, Kim G, et al. Haemophilus influenzae forms biofilms on airway epithelia: implications in cystic fibrosis. Haemophilus influenzae, serotype b invasive disease (B, acute Hepatitis B, chronic 14 1 0 (0) (17) 11 (7) 9 0 4 0 (0) (15) 8 (3) 11 0 2 0 (0) () 4 (3) 16

  Background Since the widespread use of Haemophilus influenzae (Hi) type b (Hib) vaccines among children aged. After successful introduction of anti-Haemophilus influenzae (Hi) serotype b vaccination program in Poland, invasive non-b or nontypeable H. influenzae infections have been reported more frequently alike in other countries all over the this paper, we report 2 cases of H. influenzae serotype f (Hif) meningitis with severe clinical presentations which are rarely seen in previously. A total of 1, Haemophilus influenzae isolates from cerebrospinal fluid were examined by biochemical and serological means. Most of them belonged to biotype I (%) and to serotype b (%). The relationship of biotypes I and II to the ages of the patients was shown to be significant (P. Background: Invasive infections from Haemophilus influenzae serotype a (Hia) have been reported with increasing frequency, especially among indigenous r, there are limited population-based studies of clinical severity. We studied invasive Hia infections in Alaska to determine clinical characteristics, mortality and sequelae.. Methods.

The Official Parent"s Sourcebook on Haemophilus Influenzae Serotype B by ICON Health Publications Download PDF EPUB FB2

Get this from a library. The official parent's sourcebook on haemophilus influenzae serotype B. [James N Parker; Philip M Parker; Icon Group International, Inc.] -- This book has been created for parents who have decided to make education and research an integral part of the treatment process.

Although it also gives information useful to doctors, caregivers and. Serotyping Discrepancies in Haemophilus influenzae. Type b Disease United States, Since Haemophilus influenzae type b (Hib) conjugate vaccines were introduced in the United States inthe incidence of Hib invasive disease has declined markedly (1,2).The majority of cases of Haemophilus influenzae (Hi) disease are caused by organisms with capsule types other than b or by.

Before the introduction of effective vaccines, H. influenzae serotype b (Hib) was the cause of more than 95% of cases of invasive H. influenzae disease among File Size: KB.

Merchandise Mart Plaza Suite Chicago, IL Toll free: VelocityEHS | Humantech Oak Valley Dr. Ann Arbor, MI Toll free: Canada. Haemophilus influenzae. is a small, gram-negative coccobacillus bacterium. There are at least six serotypes of. influenzae (designated types a–f) distinguished by their capsular antigens, as well as unencapsulated (nontypeable) strains.

influenzae. serotype b (Hib) was responsible for 95% of invasive. influenzaeFile Size: KB. Since the widespread use of Haemophilus influenzae capsular type b (Hib) conjugate vaccines in the United States started in (), the incidence of invasive Hib disease in children less than 5 years old has declined drastically (1, 3, 4, 7, 10), from about perchildren before to.

Haemophilus influenzae is a gram-negative coccobacillus that represents a common cause of both localized respiratory tract and systemic (bacteremic) disease in humans [1]. Non-encapsulated, non-typable strains account for the majority of H. influenzae respiratory tract disease, whereas encapsulated, serotype b strains are responsible for most.

Haemophilus influenzae, particularly H influenzae serotype b (Hib), is an important pathogen that causes serious diseases like meningitis and septicaemia.

Since the introduction of Hib conjugate vaccines in the s, the epidemiology of invasive H influenzae disease has changed substantially, with most infections now caused by non-Hib strains.

We discuss the importance of H influenzae. Haemophilus influenzae disease is a name for any illness caused by bacteria called H. of these illnesses, like ear infections, are mild while others, like bloodstream infections, are very serious. In spite of the name, H. influenzae do not cause influenza (the flu).Vaccines can prevent one type of H.

influenzae (type b or Hib) disease. Haemophilus influenzae serotype b. After the introduction of the HIB vaccine, more than half of all invasive disease is now caused by nonencapsulated (nontypeable) strains.

Haemophilus influenzae type b (these antigen tests are nonreactive for infections caused by other organisms). Dear Parents and Staff. RE: Haemophilus influenzae b (Hib) disease.

A child attending [insert name of centre] has been diagnosed with Haemophilus influenzae b (Hib) infection. Hib infection is caused by a bacterium that is carried, usually harmlessly, in the nose and throat by around 3% of people. Haemophilus influenzae (formerly called Pfeiffer's bacillus or Bacillus influenzae) is a Gram-negative, coccobacillary, facultatively anaerobic capnophilic pathogenic bacterium of the family Pasteurellaceae.

influenzae was first described in by Richard Pfeiffer during an influenza pandemic. The bacterium was argued by some to be the cause of influenza untilwhen the viral nature. Before the introduction of the conjugate vaccine, Haemophilus influenzae serotype b (Hib) was the leading cause of bacterial meningitis in children.

Although successful in reducing Hib cases, the vaccine confers no protection against other serotypes of H influenzae, such as a (Hia), or f (Hif).The emergence of invasive disease caused by non-Hib in northwestern Ontario (38 cases between Before the introduction of effective vaccines, H.

influenzae serotype b (Hib) was the cause of more than 95% of Hi among children; and the leading cause of bacterial meningitis in the United States among children younger than 5 years of age.

Haemophilus influenzae disease is caused by small gram-negative coccobacilli that may be either encapsulated (types a f) or unencapsulated (nontypeable). Type b (Hib) is the only kind for which there is a vaccine and for which control measures are considered necessary. It is the only type that is reportable.

Clinical Description. Haemophilus influenzae is a Gram-negative coccobacillus that can cause serious invasive disease in children and adults. The most prevalent strain is type b (Hib). Published 1 April Background. High, or increasing, rates of invasive Haemophilus influenzae (Hi) type a disease have been reported from North American native children from circumpolar regions, raising the question of serotype replacement being driven by vaccination against Hi type b (Hib).

Indigenous Australians from remote areas had high rates of invasive Hib disease in the past, comparable to those in North. Haemophilus influenzae is a respiratory pathogen that causes a wide spectrum of infections in humans ().

influenzae carrying a polysaccharide capsule have been an important cause of serious invasive diseases such as meningitis and septicemia in children. The majority of cases of invasive disease are caused by H. influenzae serotype b (Hib), and this has led to the introduction of nationwide.

Other studies in the Gambia have confirmed the presence of H. influenzae serotype b by recovery from percutaneous lung aspirates of children with pneumonia. 25, 26 In this sense, the epidemiological profile of Hib disease in our setting could be expected to be less invasive, i.e. non-bacteraemic disease, when compared with poorer countries.

2 The immunological basis for immunization series - Module 9: Haemophilus influenzae type b vaccines Figure 1: Age distribution of Hib infection from October to September in six regions in England and Wales 0 30 60 90 J.W. Johnston, M.A. Apicella, in Encyclopedia of Microbiology (Third Edition), Haemophilus influenzae is a Gram-negative, opportunistic pathogen that remains a significant human pathogen.

It is commonly found as a member of the normal flora of the nasopharynx. influenzae strains are distinguished by the presence of a capsule. Encapsulated strains tend to cause more invasive. INTRODUCTION. Haemophilus influenzae type b (Hib) is a major cause of invasive bacterial infection and pneumonia in childhood.

Globally, Hib is estimated to cause over 3 million cases of serious disease anddeaths, primarily among children in resource-poor countries (36, 37).Protein-polysaccharide conjugate Hib vaccines are highly effective in preventing disease when used in routine. Encapsulated Haemophilus influenzae strains belong to type-specific genetic lineages.

Reliable capsule typing requires PCR, but a more efficient method would be useful. We evaluated capsule typing by using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry.

Isolates of all capsule types (a−f and nontypeable; n = ) and isogenic capsule transformants. The incidence of severe Haemophilus influenza infections, such as sepsis and meningitis, has declined substantially since the introduction of the H.

influenzae serotype b vaccine. However, the H. influenzae type b vaccine fails to protect against nontypeable H. influenzae strains, which have be-come increasingly frequent causes of invasive disease.

Mohamad I. Idris, Chong T. Tan, in Neuroepidemiology in Tropical Health, Bacteria. Until recently, the most common causes of bacterial meningitis worldwide are Haemophilus influenzae, Streptococcus pneumonia, and Neisseria meningitides in children; S. pneumonia and certain gram-negative bacteria in adults.

With the recent introduction of the various vaccines for meningitis, there. CDC tracks invasive Haemophilus influenzae disease using 2 surveillance systems. Invasive disease refers to when the bacteria invade parts of the body, like blood, that are normally free from germs.

CDC does not track non-invasive H. influenzae disease, such as ear infections. National Notifiable Diseases Surveillance System. We describe the epidemiology of invasive Haemophilus influenzae disease during – in 12 European countries and assess overall H. influenzae disease trends by serotype and patient age.

Mean annual notification rate was cases/, population, with an increasing annual trend of % (95% CI % to %). The notification rate was highest for patients <1 month of age ( INVASIVE DISEASES CAUSED BY Hia.

Similar to Hib, most cases of systemic Hia infection are in young children (11, 17, 20, 25, 28, 29, 36, 45).Rutherford et al.

in a review of cases from to showed that meningitis was the most common disease caused by ay and Turk studied H. influenzae capsulated strains among 2, Haemophilus isolates (recovered from more t Moxon ER, Smith AL, Averill DR, Smith DH.

Haemophilus influenzae meningitis in infant rats after intranasal inoculation. J Infect Dis. Feb; (2)– Musser JM, Barenkamp SJ, Granoff DM, Selander RK.

Genetic relationships of serologically nontypable and serotype b strains of Haemophilus influenzae. The biochemical characteristics of strains of Haemophilus influenzae and 83 strains of Haemophilus parainfluenzae isolated over an month period are described.

Of 22 characteristics obtained, only 6 were necessary to biochemically identify and biotype the isolates. The key substrates or tests were urease, ornithine, indole, o-nitrophenyl-beta-D-galactopyranoside, sucrose, and xylose. Haemophilus influenzae.

Type a Meningitis in Immunocompetent Child, Oman, Technical Appendix. Technical Appendix Table. Additional research on non–serotype b.

Haemophilus influenzae (Hi) Authors Year published Location of study Subject Reference Sadeghi-Aval P, et al. Northwestern Ontario, Canada Non-Hib pediatric meningitis. 1.TY - JOUR. T1 - Haemophilus influenzae.

T2 - Drug therapy and resistance. AU - Murphy, J. E. AU - Job, M. L. PY - /1/1. Y1 - /1/1. N2 - Haemophilus influenzae (Hif) is an aerobic and facultatively anaerobic gram-negative coccobacillary microorganism which exists in encapsulated and nonencapsulated forms, both of which are capable of producing beta-lactamase.Haemophilus influenzae infection causes serious invasive disease, but incidence of the most virulent serotype, Hib, has dropped since introduction of routine Hib vaccination.

In England and Wales, the incidence of 2 other serotypes, Hie and Hif, is increasing; during –, there was an % year-on-year increase in Hif and a % increase in Hie.